Method and system for determining compound concentrations in...

Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system

Reexamination Certificate

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C324S303000, C324S306000, C324S309000, C324S318000, C324S321000

Reexamination Certificate

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07847547

ABSTRACT:
A method of determining a concentration level of a compound in a mixture is provided. A plurality of compounds are identified in the mixture based on intensity peaks identified from NMR data generated from the mixture. A compound is selected from the identified plurality of compounds for a concentration determination. A concentration equation associated with the selected compound is determined. A first peak associated with the selected compound is selected from the NMR data. The selected first peak does not overlap with a peak associated with another compound of the identified plurality of compounds. An intensity value associated with the selected first peak is determined. A concentration of the selected compound in the mixture is calculated using the determined concentration equation and the determined intensity value.

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Lewis, Ian, et al., “Method for Determining Molar Concentrations of Metabolites in Complex Solutions from Two-Dimensional1H-13C NMR Spectra,” American Chemical Society, Analytical Chemistry, vol. 79, No. 24, Dec. 15, 2007, pp. 9385-9390.

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