Metal complexes derivatized with folate for use in diagnostic an

Details Metal complexes derivatized with folate for use in diagnostic an Metal complexes derivatized with folate for use in diagnostic an

1998-05-16

2000-07-25

Dees, Jose' G.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

424 91, 424 111, 424 169, 534 10, 534 14, A61K 5100, A61M 3614

Patent

active

060933828

ABSTRACT:
Diagnostic and therapeutic compositions in the form of complexes for enhancing transmembrane transport of a diagnostic or therapeutic agent and methods for their use. The complexes contain the .alpha., .gamma., or bis isomers of folate receptor-binding analogs of folate, a metal chelated by a ligand, and in one embodiment, a chemotherapeutic agent.

REFERENCES:
patent: 4639365 (1987-01-01), Sherry
patent: 5055288 (1991-10-01), Lewis et al.
patent: 5069216 (1991-12-01), Groman et al.
patent: 5108921 (1992-04-01), Low et al.
patent: 5141739 (1992-08-01), Jung et al.
patent: 5248492 (1993-09-01), Groman et al.
patent: 5262176 (1993-11-01), Palmacci et al.
patent: 5284646 (1994-02-01), Menz et al.
patent: 5336506 (1994-08-01), Josephson et al.
patent: 5342606 (1994-08-01), Sherry et al.
patent: 5352432 (1994-10-01), Menz et al.
patent: 5358704 (1994-10-01), Desreux et al.
patent: 5373093 (1994-12-01), Vallarino et al.
patent: 5399338 (1995-03-01), Born et al.
patent: 5416016 (1995-05-01), Low et al.
patent: 5478576 (1995-12-01), Jung et al.

Affiliated with

Also associated with

Rating

Metal complexes derivatized with folate for use in diagnostic an does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Metal complexes derivatized with folate for use in diagnostic an, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Metal complexes derivatized with folate for use in diagnostic an will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1334578