Membrane filter for capturing circulating tumor cells

Details Membrane filter for capturing circulating tumor cells Membrane filter for capturing circulating tumor cells

2006-04-20

2010-12-07

Warden, Jill (Department: 1797)

Chemical apparatus and process disinfecting, deodorizing, preser

Control element responsive to a sensed operating condition

C210S490000, C210S500260, C210S506000, C210S767000, C210S435000, C422S091000, C435S004000, C435S366000, C435S283100

Reexamination Certificate

active

07846393

ABSTRACT:
The present invention provides a parylene-based membrane filter device for capturing of circulating tumor cells (CTC). The membrane filter has an array of holes having a predetermined geometric design with precisely controlled size, shape and density. In one aspect, the device has a stack of substantially parallel membrane filters with uniformly-spaced and/or monodispersed holes.

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Kahn, H.J. et al., “Enumeration of circulating tumor cells in the blood of breast cancer patients after filtration enrichment: correlation with disease stage,”Breast Cancer Research and Treatment, 2004, vol. 86, pp. 237-247.

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