Mammaglobin, a mammary-specific breast cancer protein

Details Mammaglobin, a mammary-specific breast cancer protein Mammaglobin, a mammary-specific breast cancer protein

1996-09-30

1999-01-05

Kemmerer, Elizabeth C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

4241841, 530350, 530330, G01N 3353, C07K 706, C07K 14435

Patent

active

058558896

ABSTRACT:
A purified and isolated DNA sequence and the encoded mammary-specific protein, mammaglobin, are disclosed. Also disclosed are methods for the detecting breast cancer based upon the overexpression and secretion of mammaglobin by breast cancer cells. The methods detect and/or quantitate the presence of mammaglobin or the mRNA encoding mammaglobin.

REFERENCES:
patent: 5668267 (1997-09-01), Watson et al.
Daniel et al. Mapping of linear antigenic sites on the S glycoprotein of a neurotropic murine coronavirus with synthetic peptides: a combination of nine predictive algorithms fails to identify relevant epitopes and peptide immunogenicity is drastically i, 1994.
Hopp et al. Prediction of protein antigenic determinants from amino acid sequences. Proceedings of the National Academy of Scinces, USA. vol. 78, No. 6, pp. 3824-3828, Jun. 1981.
Peeters et al. Structural studies on rat prostatic binding protein. European Journal of Biochemistry. vol. 115, pp. 115-121, 1981.
Watson et al. Isolation of differentially expressed sequence tags from human breast cancer. Cancer Research. vol. 54, pp. 4598-4602, Sep. 1, 1994 .

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