Macrolide antibiotic

Details Macrolide antibiotic Macrolide antibiotic

1980-10-21

1983-02-22

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

043747647

ABSTRACT:
Macrolide antibiotics are derivatives of the compound Mycoplanecin and have the formula: ##STR1## (in which R represents a hydrogen atom or an N-(.alpha.-hydroxybutyryl)-N-methylvalyl group). The compound in which R represents an N-(.alpha.-hydroxybutyryl)-N-methylvalyl group can be prepared by reducing Mycoplanecin and the compound in which R represents a hydrogen atom can be prepared by the hydrolysis of Mycoplanecin or of the compound of formula (I) in which R represents an N-(.alpha.-hydroxybutyryl)-N-methylvalyl group.

REFERENCES:
patent: 3365362 (1968-01-01), Mancy et al.
patent: 3719656 (1973-03-01), Jolles
patent: 4108985 (1978-08-01), Ruegger et al.

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