Macrocycles useful in the treatment of alzheimer's disease

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C540S456000

Reexamination Certificate

active

07456163

ABSTRACT:
The present invention is macrocycles of the formula (X):for treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme for the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.

REFERENCES:
patent: 6043357 (2000-03-01), Abbenante et al.

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