Live Newcastle disease virus vaccines

Details Live Newcastle disease virus vaccines Live Newcastle disease virus vaccines

1976-03-01

1977-10-11

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 89, A61K 3932, A61K 4100

Patent

active

040535835

ABSTRACT:
The improved live Newcastle disease virus vaccines of the invention contain a cold or cold and temperature-sensitive strain of Newcastle disease virus obtained by U.V. or nitrous acid mutation. The vaccines are administered to chickens in the form of an aerosol.

REFERENCES:
clavell et al., Chem. Abstr. 75 No. 137866e(1971) of J. Virol. 8(4): 500-8(1971) "Relation Between the Ribonucleic Acid-Synthesizing Capacity of Ultraviolet-Irradiated Newcastle Disease Virus and Its Ability to Induce Interferon."
Huppert et al., Chem. Abstr. 76 No. 84168R(1972) of Biol. Large RNA Viruses, Symp. 1969: pp. 482-492, Pub. 1970 "Newcastle Disease Virus RNA Synthesis in Cells Infected with Unirradiated or UV-Irradiated Virus."
Meager et al., Nature 235: pp. 280-282 Feb. 4, 1972 "Production of Interferon by Ultraviolet Radiation Inactivated Newcastle Disease Virus."
Preble et al., Chem. Abstr. 76 No. 96836v(1972) of J. Virol 9(2): pp. 200-206 (1972) and Chem. Abstr. 79 No. 89428x(1973) of J. Virol. 12(3): pp. 472-480 (1973) "Temperature-Sensitive Mutants Isolated From L Cells Persistently Infected with Newcastle Disease Virus."

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