Liquid pharmaceutical composition

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C424S439000, C514S779000, C514S974000

Reexamination Certificate

active

06930119

ABSTRACT:
This invention relates to new pharmaceutical compositions and methods for their preparation, and in particular it relates to taste-masked liquid compositions comprising a solution of a histamine H2-antagonist complexed with an alginate and also containing a humectant. The solution is buffered to a pH of between about 6 to 7. The inventive solution may be flavored and sweetened and preserved.

REFERENCES:
patent: 3492131 (1970-01-01), Schlatter
patent: 4996222 (1991-02-01), Carlin et al.
patent: 5007790 (1991-04-01), Shell
patent: 5456918 (1995-10-01), Quirk et al.
patent: 5811123 (1998-09-01), Fuisz
patent: 5976578 (1999-11-01), Beyerle et al.
patent: 39 31 215 (1990-03-01), None
patent: WO 95 01780 (1995-01-01), None
patent: WO 95 01795 (1995-01-01), None
Washington N et al., “Effect of Alginate and Alginate-Cimetidine Combination Therapy on Stimulated Postprandial Gastro-Oesophageal Reflux.” Journal of Pharmacy and Pharmacology, London, GB, vol. 47, no. 11, pp. 879-882 (1995).

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