Liquid chromatography system with solvent proportioning

Measuring and testing – Liquid analysis or analysis of the suspension of solids in a... – Content or effect of a constituent of a liquid mixture

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210198C, G01N 3108

Patent

active

039850196

ABSTRACT:
A liquid chromatography system including a liquid chromatography column, first and second reservoirs for solvents to be utilized as the mobile phase, reciprocating pumping means for flowing the solvents through the column, and motor means for driving the pump through successive pumping cycles including pump and fill subcycles. First and second solenoid-actuated proportioning valves are positioned at the low pressure side of the pump, i.e. between the first and second reservoirs and the pump inlet. Gradient setting means are provided for setting a preselected solvent proportion to be used over a time period. Means responsive to the gradient setting opens one of the said proportioning valves during a predetermined portion of the fill subcycle. The valves are actuated in complementary fashion with respect to opening and closing; hence the fill subcycle is divided between flow proceeding from the first and second valves in accordance with the gradient setting.

REFERENCES:
patent: 3446057 (1969-05-01), Bakalyar et al.
patent: 3537585 (1970-11-01), Waters
patent: 3701609 (1972-10-01), Bailey
patent: 3855129 (1974-12-01), Abrahams et al.
patent: 3934456 (1976-01-01), Munk

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