Organic compounds -- part of the class 532-570 series – Organic compounds – Silicon containing
Patent
1992-07-17
1994-12-20
Dees, Jose G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Silicon containing
556419, 528 22, 528 31, 528 38, 2101982, 210679, C07F 702, C08G 7712
Patent
active
053747550
ABSTRACT:
Novel carbamate compounds, novel silylcarbamate compounds and novel reversed phase materials comprising a silica substrate modified with a modified novel silylcarbamate compound are disclosed which may, for example, be used as stationary phases for liquid chromatography applications. Attached to the carbamate group are several reversed or normal phase producing groups such as cyanoalkyl, tertiary butyl, dibutyl, octyl, dodecyl, tetradecyl, octadecyl or benzyl. The new stationary phases may be endcapped with a short chain alkyl silane. One particular advantage of these stationary phases is decreased interaction with basic samples due to shielding of the unreacted silanol groups on the silica surface. The new phases are particularly useful in the chromatographic analysis of basic samples or more generally for samples having an undesirable interaction with the unmodified silanols.
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Neue Uwe D.
Niederlaender Carsten L.
Petersen John S.
Cook Paul J.
Dees Jos,e G.
Jones Huw R.
Karnakis Andrew T.
Millipore Corporation
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