Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1994-10-25
1996-08-20
Kim, Kay K. A.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
514 8, 514 21, 525 541, 5303911, 5303919, 530399, 530408, 530409, 530345, 536 64, 536 221, 540304, 540350, 540351, 540478, 549298, A61K 3944, C07K 1706, C07K 15252, C07K 1906
Patent
active
055476678
ABSTRACT:
Conjugates of general formula 1:
REFERENCES:
patent: 5387578 (1995-02-01), Angelucci et al.
Takahashi et al (1984) Iyo Masu Kenkyukai Koenshu 9:77-82.
Webb et al (1990) Polymer Prep. (Am. Chem. Soc., Div. Polym. Chem) 31(2):204-205.
The Journal of Biological Chemistry, vol. 264, No. 25, Sep. 1989, (US) D. M. Neville et al.: "Enhancement of immunotoxin efficacy by acid-clevable cross-linking agents utilizing diphteria toxin and toxen mutants", pp. 14653-14661, see the whole article.
Angelucci Francesco
Bersani Laura
Caruso Michele
Ripamonti Marina
Ruggieri Daniela
Farmitalia Carlo Erba S.r.l.
Kim Kay K. A.
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