Lincomycin derivatives and antimicrobial agents comprising...

Details Lincomycin derivatives and antimicrobial agents comprising... Lincomycin derivatives and antimicrobial agents comprising...

2011-02-01

2011-02-01

McIntosh, III, Traviss C (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S016200, C536S016300, C536S016400, C536S016500

Reexamination Certificate

active

07879808

ABSTRACT:
An objective of the present invention is to provide compounds of formula (1) or their pharmacologically acceptable salts or solvates wherein A represents aryl; R1represents N-optionally substituted C1-6alkyl-N-optionally substituted C1-6alkylamino-C1-6alkyl; R2represents a hydrogen atom or optionally substituted C1-6alkyl; R3represents optionally substituted C1-6alkyl or C3-6cycloalkyl-C1-4alkyl; m is 1 to 3; n is 0; and p is 0 to 2. The compounds are novel lincomycin derivatives that have a potent activity against resistantStreptococcus pneumoniae, which have recently posed problems, in the treatment of infectious diseases. Further, the compounds are usable as antimicrobial agents and are useful for preventing or treating bacterial infectious diseases.

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