Lazaroid-based compositions and method for preventing adhesion f

Details Lazaroid-based compositions and method for preventing adhesion f Lazaroid-based compositions and method for preventing adhesion f

1994-11-17

1997-03-25

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514249, A61K 3156, A61K 31495

Patent

active

056145152

ABSTRACT:
Compositions and method for the minimization or prevention of adhesion formation, whereby an effective amount of at least one lazaroid compound, preferably one of general formula I, is administered for a period of time sufficient to permit tissue repair. The compound of general formulae I or II is preferably administered in conjunction with a delivery vehicle (e.g., microcapsules, microspheres, biodegradable polymer films, lipid-based delivery systems such as liposomes and lipid foams, viscous instillates and absorbable mechanical barriers) useful for maintaining local concentrations of the compound at an effective level.

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