Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-05-13
2008-05-13
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S119000, C546S120000
Reexamination Certificate
active
11623367
ABSTRACT:
The present application describes lactam-containing compounds and derivatives thereof of Formula I:in-line-formulae description="In-line Formulae" end="lead"?P4-P-M-M4Iin-line-formulae description="In-line Formulae" end="tail"?or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
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Han Wei
Koch Stephanie L
Lam Patrick Y. S.
Li Yun-Long
Orwat Michael J.
Bristol--Myers Squibb Company
Fitzpatrick ,Cella, Harper & Scinto
Kifle Bruck
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