L-Lysine-producing corynebacteria and process for the...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

Reexamination Certificate

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C435S320100, C435S252320

Reexamination Certificate

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07094584

ABSTRACT:
The invention relates to L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dihydrodipicolinate reductase gene) and the pyc gene, but especially the dapA gene and the lysC gene (aspartate kinase gene), are enhanced and, in particular, over-expressed, and to a process for the preparation of L-lysine.

REFERENCES:
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patent: 6861246 (2005-03-01), Kreutzer et al.
patent: 2003/0049804 (2003-03-01), Pompejus et al.
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patent: 01108790 (2001-06-01), None
patent: WO 01 00 843 (2001-01-01), None
Eikmanns et al., EMBL Database Acc. No. X67737, Apr. 1, 1993.
Hungarian Search Report, P0002585, Jun. 27, 2002.

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