L-gulono-gamma-lactone-dehydrogenase for producing vitamin C

Details L-gulono-gamma-lactone-dehydrogenase for producing vitamin C L-gulono-gamma-lactone-dehydrogenase for producing vitamin C

1991-09-17

1993-10-05

Naff, David M.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

435118, 435125, C12N 904, C12P 1716, C12P 1706

Patent

active

052504280

ABSTRACT:
The present invention concerns a novel process for the microbiological manufacture of L-ascorbic acid from L-gulono-gamma-lactone, a process for preparing the enzyme being responsible for the microbiological oxidation of L-gulono-gamma-lactone, and said enzyme as a homogeneous protein, which is a L-gulono-gamma-lactone dehydrogenase.

REFERENCES:
Shigeoka, Shigeru et al., "The Effect of Illumination on the L-Ascorbic Acid Content in Euglena gracilis z," Agric. Biol. Chem. (43), pp. 2053-2058, 1979.
Nishiki et al., Arch. Biochem. Biophy., 175, 427-435, (1976).
Nishiki et al., Biochemistry, 21, 5076-5082, 1982.
Nishiki et al., Arch. Biochem. Biophy., 191, 479-486, 1978.
Bleeg et al., Dur. J. Biochem., 127, 391-396, 1982.
Shigeoka et al., Agric. Biol. Chem., 43, 2187-2188, (1979).

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