Ketamine treatment of restless legs syndrome

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S400000, C424S451000, C424S464000, C424S078020, C514S183000, C514S289000, C514S450000

Reexamination Certificate

active

06855735

ABSTRACT:
The present invention is directed to a method for treating symptoms associated with Restless Legs Syndrome (RLS). The method includes administering to a warm-blooded animal in need of such treatment a dose of ketamine sufficient to alleviate symptoms associated with RLS.

REFERENCES:
patent: 5296507 (1994-03-01), Tanaka et al.
patent: 5395831 (1995-03-01), Gemmill, Jr. et al.
patent: 5612380 (1997-03-01), Lerner et al.
patent: 5800385 (1998-09-01), Demopulos et al.
patent: 5877173 (1999-03-01), Olney et al.
patent: 5976547 (1999-11-01), Archer et al.
patent: 6056715 (2000-05-01), Demopulos et al.
patent: 6184218 (2001-02-01), Evenden et al.
patent: 6184219 (2001-02-01), Evenden et al.
patent: 6194000 (2001-02-01), Smith et al.
patent: 6210394 (2001-04-01), Demopulos et al.
patent: 6248789 (2001-06-01), Weg
patent: 6265414 (2001-07-01), Harris et al.
patent: 6303573 (2001-10-01), Ruoslahti et al.
patent: 6310085 (2001-10-01), Willis
patent: 6316403 (2001-11-01), Pinsky et al.
patent: 6319927 (2001-11-01), Martin
patent: 6323215 (2001-11-01), Macielag et al.
patent: 6350470 (2002-02-01), Pather et al.
patent: 6436974 (2002-08-01), Belliotti et al.
patent: 20020072538 (2002-06-01), Chenard et al.
patent: 4340767 (1995-06-01), None
Polydefkins et al, Subclinical sensory neuropathy in late-onset restless legs syndrome, Neurology, Oct. 24, 2000 55(8): 1115-21.*
Patel (Anesthesia Anal., 70 (6), pp. 635-44, Jun. 1990).*
Bowdle et al, Psychedelic effects of ketamine in healthy volunteers: relationship to steady-state plasma concentrations, Anesthesiology. 1998, vol. 88 (1), 82-88.*
Kawasaki, Kawasaki, Ogata, Nandate and Shigematsu, “Canadian Journal of Anaesthesia,” vol. 48(8), pp. 819-823 dated Sep. 2001 (Abstract Only).
Kawamata, Omote, Sonoda, Kawamata and Namiki, “Anesthesiology,” vol. 93(2), pp. 520-528 dated Aug. 2000 (Abstract Only).
Radu, Bordin, Weber and Lindefors, “Brain Research,” vol. 908(2), pp. 197-203 dated Jul. 27, 2001 (Abstract Only).
Tang, Rao, Hu and Wang, “Chung-Kuo Yao Li Hsueh Pao-Acta Pharmacologica Sinica,” vol. 21(9), pp. 819-823 dated Sep. 2000 (Abstract Only).
Pieta, Millar, Zacharias, Fine and Kryger, “Effect of Pergolide on Restless Legs and Leg Movements in Sleep in Uremic Patients,” vol. 21(6), pp. 617-622 dated Sep. 15, 1998 (Abstract Only).
Trenkwalder, Stiasny and Oertel, “Therapy of Idiopathic and Uremic Restless Legs Syndrome,” vol. 67(4), pp. 265-276 dated Sep. 1996 (Abstract Only).
Montplaisir, Denesle, Petit, “Pramipexole in the Treatment of Restless Legs Syndrome: A Follow-Up Study,” vol. 7 suppl. 1, pp. 27-31 dated May 2000 (Abstract Only).
Stiasny, Wetter, Trenkwalder and Oertel, “Restless Legs Syndrome and Its Treatment by Dopamine Agonists,” vol. 7(1), pp. 21-25 dated Nov. 1, 2000 (Abstract Only).
Lauema, “Nocturnal Wandering Caused by Restless Legs and Short-Acting Benzodiazepines,” vol. 83(6), pp. 492-493 dated Jun. 1991 (Abstract Only).
Glasauer, “Restless Legs Syndrome,” vol. 39(3), pp. 125-133 dated Mar. 2001 (Abstract Only).
Earley, Allen, Beard and Connor, “Insight into the Pathophysiology of Restless Legs Syndrome,” vol. 62(5), pp. 623-628 dated Dec. 1, 2000 (Abstract Only).
Freye and Levy, “Acute Abstinence Syndrome Following Abrupt Cessation of Long-Term Use of Tramadol (Ultram): A Case Study,” vol. 4(3), pp. 307-311 dated 2000 (Abstract Only).
Tan and Ondo, “Restless Legs Syndrome: Clinical Features and Treatment,” vol. 319(6), pp. 397-403 dated Jun. 2000 (Abstract Only).
Walters, et al., “Long-Term Follow-Up On Restless Legs Syndrome Patients Treated with Opioides,” vol. 16(6), pp. 1105-1109 dated Nov. 2001 (Abstract Only).
Tergau, Wischer, Wolf and Paulus, “Treatment of Restless Legs Syndrome with the Dopamine Agonist Alpha-dihydroergocryptine,” vol. 16(4), pp. 731-735 dated Jul. 2001 (Abstract Only).
Danoff, Grasso, Terry and Flynn, Pleuropulmonary Disease Due to Pergolide Use for Restless Legs Syndrome, vol. 120(1), pp. 313-316 dated Jul. 2001 (Abstract Only).
Akata, Izumi and Nakashima, “Mechanisms of Direct Inhibitory Action of Ketamine on Vascular Smooth Muscle in Mesenteric Resistance Arteries,” vol. 95(2), pp. 452-462 dated Aug. 2001 (Abstract Only).
Allen and Earley, “Restless Legs Syndrome: A Review of Clinical and Pathopysiologic Features,” vol. 18(2), pp. 128-147 dated Mar. 2001.
Paulson, “Restless Legs Syndrome How to Provide Symptom Relief with Drug and Nondrug Therapies,” vol. 55(4), pp. 35-38,43-44,47-48 dated Apr. 2000 (Abstract Only).
Evidente, Adler, Caviness, Hentz and Gwinn-Hardy, “Amantadine is Beneficial in Restless Legs Syndrome,” vol. 15(2), pp. 324-327 dated Mar. 2000 (Abstract Only).
Kraus, Shuld and Pollmacher, “Periodic Leg Movements in Sleep and Restless Legs Syndrome Probably Caused by Olanzapine,” vol. 19(5), pp. 478-479 dated Oct. 1999 (Abstract Only).
Adler, “Treatment of Restless Legs Syndrome with Gabapentin,” vol. 20(2), pp. 148-151 dated Apr. 1997 (Abstract Only).
Chaudhuri, et al., “Restless Legs Syndrome,” vol. 71(2), pp. 13-146 dated Aug. 2001.
Rastaldo, Penna and Pagliaro, “Comparison Between the Effects of Pentobarbital or Ketamine/Nitrous Oxide Anesthesia on Metabolic and Endothelial Components of Coronary Reactive Hyperemia,” vol. 69(6), pp. 729-738 dated Jun. 29, 2001 (Abstract Only).
Ogawa, Tanaka and Murray, “Inhibitory Effects of Etomidate and Ketamine on Endothelium-Dependent Relaxation in Canine Pulmonary Artery,” vol. 94(4), pp. 668-677 dated Apr. 2001 (Abstract Only).
Evidente and Adler, “How to Help Patients with Restless Legs Syndrome. Discerning the Indescribable and Relaxing the Restless,” vol. 105(3), pp. 59-61, 65-66, 73-74 dated Mar. 1999(Abstract Only).
Lauerma and Markkula, “Treatment of Restless Legs Syndrome with Tramadol: An Open Study,” vol. 60(4), pp. 241-244 dated Apr. 1999 (Abstract Only).
Ehrenberg, Eisensehr, Corbett, Crowley and Walters, “Valproate for Sleep Consolidation in Periodic Limb Movement Disorder,” vol. 20(5), pp. 574-578 dated Oct. 2000 (Abstract Only).
Wetter and Pollmacher, “Restless Legs and Periodic Leg Movements in Sleep Syndromes,” vol. 244 (4 Suppl. 1), pp. S37-45 dated Apr. 1997 (Abstract Only).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Ketamine treatment of restless legs syndrome does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ketamine treatment of restless legs syndrome, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ketamine treatment of restless legs syndrome will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3467718

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.