Keratinocytes useful for the treatment of wounds

Details Keratinocytes useful for the treatment of wounds Keratinocytes useful for the treatment of wounds

2007-07-24

2007-07-24

Lankford, Jr., Leon B. (Department: 1657)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Primate cell, per se

C435S325000, C435S366000, C424S093700

Reexamination Certificate

active

10268496

ABSTRACT:
The invention relates to new keratinocytes which may be cultured in vitro and the advantageous use thereof for preparing a product which can be used to treat acute and chronic wounds.

REFERENCES:
patent: 4016036 (1977-04-01), Green et al.
patent: 5292655 (1994-03-01), Wille, Jr.
patent: 5298417 (1994-03-01), Cancedda et al.
patent: 5658331 (1997-08-01), Della Valle et al.
patent: 5693332 (1997-12-01), Hansbrough
patent: 5891617 (1999-04-01), Watson et al.
patent: 6485971 (2002-11-01), Kaur et al.
patent: 6585969 (2003-07-01), Van Bossuyt
patent: 19917532 (2000-10-01), None
patent: 0 462 426 (1991-12-01), None
patent: WO 93/10217 (1993-05-01), None
patent: WO 96/24018 (1996-08-01), None
patent: WO 99/47644 (1999-09-01), None
Graziella Pellegrini et al; Location and Clonal Analysis of Stem Cells and Their Differentiated Progeny in the Human Ocular Surface; Journal of Cell Biology vol. 145 No. 4 May 17, 1999, pp. 769-782; the Rockefeller University Press.
Graziella Pellegrini et al; p63 identifies keratinocyte stem cells; Laboratory of Tissue Engineering IDI Mar. 13, 2001 vol. 98 No. 6 pp. 3156-3161; PNAS.
G. Pellegrini et al; Cultivation of human keratinocyte stem cells: current and future clinical applications; Medical Biological Engineering & Computing 1998 vol. 36 pp. 778-790; Laboratory of Tissue Engineering I.D.C.
Cosima Harle-Bachor et al; Tetomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived skin keratinocytes; Cell Biology Jun. 1996 vol. 93 pp. 6476-6481;Proc. Natl. Acad. Science USA.
J. Donald Weaver et al; Partial Trisomies in two Spontaneously Arising Long-Lived Human Keratinocyte Lines; In Vitro Cell Dev. Biology Aug. 1991 vol. 27A pp. 670-675; Tissue Culture Association.
Petra Boukamp et al; Normal Keratinization in a Spontaneously Immortalized Aneuploid Human Keratinocyte Cell Line; The Journal of Cell Biology Mar. 1988 vol. 106 pp. 761-771: The Rockefeller University Press Copy of International Search Report Reference #PCT/EP 02/11459.
Maier, K., “Transplantation von in-vitro-Epidermis-Chancen und Risiken”; Quintessenz 3, pp. 289-304.
Teepe, R. G. C., et al; “Randomized trial comparing cryopreserved cultured epidermal allografts with hydrocolloid dressings in healing chronic venous ulcers”; Journal of the American Academy of Dermatology; 9/6; 1993, pp. 982-988.
Beele, H. et al; “Repeated cultured epidermal allografts in the treatment of chronic leg ulcers of various origins”; Dermatologica, 183 (1), 1991, pp. 31-5.
DeLuca, M. et al; “Treatment of leg ulcers with cryopreserved allogeneic cultured epithelium. A multicenter study”; Archives of Dermatology, 128(5), 1992, pp. 633-638.
Falanga, V. et al; “Rapid healing of venous ulcers and lack of clinical rejection with an allogeneic cultured human skin equivalent”: Archives of Dermatology, 134, 1998, pp. 293-300.
Harris, P. A. et al; “Use of hyaluronic acid and cultured autologous keratinocytes and fibroblasts in extensive burns”: Lancet 353, 1999, pp. 35-36.
Lam, P. K. et al; “Development and evaluation of a new composite Laserskin graft”, J of Trauma: Injury, Infection and Cricital Care. 47, 1999. pp. 918-922.
Lang, E. et al; “Rapid normalization of epidermal integrin expression after allografting of human keratinocytes”; J of Investigative Dermatology, 107, 1996, pp. 423-427.
Leigh, I. M. et al; “Clinical practice and biological effects of keratinocyte grafting”; Annals of the Academy of Medicine, 20(4), 1991.
Lindgren, C. et al, “Treatment of venous leg ulcers with cryopreserved cultured allogeneic keratinocytes: a prospective open controlled study”; British Journal of Dermatology, 139(2), 1998, pp. 271-275.
Phillips, T. J. et al: “Cultured allogenic keratinocyte grafts in the management of wound healing: prognostic factors”, Journal of Dermatologic Surgery and Oncology: 15(11), 1989.
Schoenfeld, J. et al; “Keratinozyten aus der Zellkultur zur Therapie von Hautdefekten”; Hautarzt, 44, 1993, pp. 281-289.
Tanczos, E. et al: “Keratinozytentransplantation and Tissue Engineering. Neue Ansatze in der Behandlung chronlscher Wunden”; Zentralbl Chir. 124. Supp 1: 1999, pp. 81-86.

Affiliated with

Also associated with

Rating

Keratinocytes useful for the treatment of wounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Keratinocytes useful for the treatment of wounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Keratinocytes useful for the treatment of wounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3795392