Kappa agonist compounds and pharmaceutical formulations thereof

Details Kappa agonist compounds and pharmaceutical formulations thereof Kappa agonist compounds and pharmaceutical formulations thereof

2007-11-13

2007-11-13

Padmanabhan, Sreeni (Department: 1617)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S359000, C514S408000, C514S410000, C514S424000

Reexamination Certificate

active

10455545

ABSTRACT:
Compounds having kappa opioid agonist activity, compositions containing them and 5 method of using them as analgesics and pruritic agents are provided.The compounds of formulae I, II, III and IV have the structure:whereinX, X4, X5, X7, X9;R1, R2, R3, R4; andY, Z and n are as described in the specification.

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