Kappa agonist compounds and pharmaceutical formulations thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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514424, 514429, 548413, 548541, 548578, A61K 3140, C07D20704

Patent

active

057444587

ABSTRACT:
Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics are provided.
The compound of formula II has the structure: ##STR1## wherein X.sub.4, X.sub.5 ;

REFERENCES:
patent: 4065573 (1977-12-01), Lednicer
patent: 4098904 (1978-07-01), Szmuszkovicz
patent: 4145435 (1979-03-01), Szmuszkovicz
patent: 4212878 (1980-07-01), Lednicer et al.
patent: 4359476 (1982-11-01), Kaplan et al.
patent: 4438130 (1984-03-01), Kaplan
patent: 4663343 (1987-05-01), Horwell et al.
patent: 4855316 (1989-08-01), Horwell et al.
patent: 4906655 (1990-03-01), Horwell et al.
McMahon et al., TINS, vol. 15, No. 12 (1992).
Bernstein et al., Journal of Investigative Dermatology, 78: 82-83 (1982).
Ballantyne et al., Pain, 33: 149-160 (1988).
J. D. Bernhard, J. Am. Acad. Derm. 24: 309 (1991).
IASP Newsletter, Sep./Oct. 1996.
Thomas et al., Brain Research, 695: 267-270 (1995).
CA 115: 8474w Naphto and benzo . . . benzeneacetamide. Freeman et al., p. 827. 1991.
CA 120: 544309e DuP 747: structure activity relationship study. Rajagopalan et al.p. 968. 1994.

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