Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1996-12-19
1999-11-02
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
4352523, 4353201, 435325, 536 232, 935 22, C12N 916, C12N 120, C12N 500, C07H 2104
Patent
active
059768525
ABSTRACT:
This invention concerns novel receptor protein tyrosine phosphatase polypeptides. Specifically, this invention concerns the novel receptor protein tyrosine phosphatase .lambda. which is related to the homotypically adhering receptor protein tyrosine phosphatases .kappa. and .mu.. The invention further relates to analogs of these polypeptides in other mammals, functional derivatives thereof, antibodies which are capable of specifically binding to these polypeptides, nucleic acids encoding these polypeptides, vectors containing and capable of expressing such nucleic acid and recombinant host cells transformed with such nucleic acid. Methods for the recombinant production of these receptor protein tyrosine phosphatase polypeptides and assays for identifying agonists and antagonists of these polypeptides are also within the scope of the invention.
REFERENCES:
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Cheng Jill
Lasky Laurence A.
Dreger Walter H.
Genentech Inc.
Stole Einar
Wax Robert A.
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