Isoxazol amides of 4-hydroxy-6H-thieno[2,3-b]thiopyran-5-carboxy

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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C07D49504

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041275853

ABSTRACT:
This invention relates to novel amides of 4-hydroxy-6H-thieno[2,3-b]thiopyran-5-carboxylic acid-7,7-dioxide having the Formula I: ##STR1## wherein R.sub.1 is hydrogen, halogen or lower alkyl; R.sub.2 is hydrogen, lower alkyl or aryl; Ar is aryl or heterocyclic; to the pharmaceutically acceptable salts thereof; and to processes for their preparation. The compounds of this invention exhibit antiinflammatory activity.

REFERENCES:
patent: 3978073 (1976-08-01), Fabian et al.
patent: 4018762 (1977-04-01), Fabian et al.
patent: 4092325 (1978-05-01), Sircar et al.

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