Isoquinoline derivative

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546 15, 546270, 546334, 546335, 549336, A61K21726

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active

048249521

ABSTRACT:
An isoquinoline derivative of the following formula: ##STR1## wherein R.sub.1 is a methyl or a methoxymethyl group and R.sub.2 and R.sub.3 are each a hydrogen atom or a methyl, ethyl, methoxy, a cyclohexyl, a phenyl, a 3,4-dimethoxyphenyl, a pyridyl or an oxo (.dbd.O) group;
and therapeutically acceptable salts thereof which exhibit a low toxicity and a wide range of safety and are highly useful as a cardiotonic medication.

REFERENCES:
patent: 4260763 (1981-04-01), Bartmann et al.
Stedman's Medical Dictionary, 24th ed., Willians & Wilkins, Baltimore, pp. 226-227.
Yukhnevich et al., "Chemical Abstracts", vol. 80, 1974, col. 82596n.
Pastors, "Chemical Abstracts", vol. 85, 1976, col. 85:32778f.

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