Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.
Reexamination Certificate
2005-10-11
2005-10-11
Weber, Jon (Department: 1653)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Hormones, e.g., prolactin, thymosin, growth factors, etc.
C530S324000, C530S350000, C530S412000, C530S416000, C530S417000, C435S069100, C435S069400, C435S070100, C435S071100
Reexamination Certificate
active
06953844
ABSTRACT:
Methods are provided for large scale purification of neurotrophins, including mature NGF, suitable for clinical use. The methods provide means to separate neurotrophins from various less desirable misprocessed, misfolded, size, glycosylated, or charge forms. Compositions of neurotrophins, including mature NGF, substantially free of these variants are also provided.
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Beck Joanne T.
Burton Louis E.
Schmelzer Charles H.
Agarwal Atulya R.
Dreger Ginger R.
Fox James A.
Genentech Inc.
Mohamed Abdel A.
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