Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1993-08-18
1995-04-04
Russel, Jeffrey E.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
435 697, 530344, 530359, 530417, 530848, C07K 114, C07K 320, C07K 1506
Patent
active
054039150
ABSTRACT:
Methods are provided for the isolation and purification of recombinant lung surfactant protein. The methods involve a multistep procedure including extraction with a C.sub.1 -C.sub.4 aliphatic alcohol and chromatographic purification steps which employ a C.sub.1 -C.sub.4 aliphatic alcohol as eluant. Purified proteins obtained using the disclosed isolation and purification steps are provided as well.
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Benson Bradley J.
Buckley Douglas
Lesikar David
Naidu Asha
Silverness Kate B.
Russel Jeffrey E.
Scios Nova Inc.
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