Intermediates in the synthesis of cephalosporins

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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540222, 540226, 540227, C07D50106

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056398778

ABSTRACT:
Novel amidine salts of 7-Amino-3-hydroxymethyl-3-cephem-4-carboxylic acid (=HACA), particular guanidine and diaza-bicyclo-alkylene salts, are useful as intermediates in the synthesis of cephalosporins.

REFERENCES:
patent: 4430498 (1984-02-01), Heusler et al.
patent: 4560749 (1985-12-01), Spry
The Journal of Antibiotics vol. 45, No. 5, pp. 721-734 (1992).
Tetrahedron vol. 41, No. 22, pp. 5133-5139, 1985.
Chemical Abstracts, 14297s, vol. 114, p. 738 1991.

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