Intermediates for production of benzothiazine carboxamides

Details Intermediates for production of benzothiazine carboxamides Intermediates for production of benzothiazine carboxamides

1983-04-25

1984-09-04

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 49, C07D27902, C07D40112, C07D51314, C07D51322

Patent

active

044698666

ABSTRACT:
A novel compound of the formula ##STR1## wherein R is hydrogen, benzyl or (C.sub.1 -C.sub.3)alkyl; R.sup.1 is benzyl or (C.sub.1 -C.sub.4)alkyl and Z.sup.1 taken together with --C.dbd.N-- forms a heterocyclic group Z where Z is 2-pyridyl, alkyl substituted-2-pyridyl, 2-thiazolyl, 2-thiazolyl substituted by one or two alkyl groups or 5-alkyl-3-isoxazolyl, each alkyl having from one to four carbon atoms; and a novel process employing the above compounds as intermediates for production of known anti-inflammatory agents of the formula ##STR2##

REFERENCES:
patent: 3346572 (1967-10-01), Shavel et al.
patent: 3591584 (1971-07-01), Lombardino
patent: 3787399 (1974-01-01), Rasmussen
patent: 3853862 (1974-12-01), Lombardino
patent: 3891637 (1975-06-01), Lombardino
patent: 3923801 (1975-12-01), Rasmussen
patent: 4289879 (1981-09-01), Lombardino
patent: 4309427 (1982-01-01), Lombardino

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