Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
2008-08-27
2010-02-02
Sullivan, Daniel M (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
C544S324000, C544S358000
Reexamination Certificate
active
07655797
ABSTRACT:
The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades. Certain disclosed embodiments concern contacting compounds having a formulaor a salt or N-oxide thereof, with 2,4-dichloro-5-fluoropyrimidine under conditions to provide compounds having a formula
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Argade Ankush
Bhamidipati Somasekhar
Clough Jeffrey
Holland Sacha J.
Keim Holger
Diehl James J.
Klarquist & Sparkman, LLP
Nwaonicha Chukwuma O
Rigel Pharmaceuticals Inc.
Sullivan Daniel M
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