Injectable drug delivery system and method

Details Injectable drug delivery system and method Injectable drug delivery system and method

1997-04-10

1998-07-21

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424435, 523105, 523113, A61F 202, A61K 600

Patent

active

057832056

ABSTRACT:
The present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then delivered, preferably by injection, into the tissue pocket at a physiologically compatible elevated temperature. Once the bioerodible material is injected into the pocket, the material cools to the body temperature of the pocket. As it cools, the material hardens and remains in place in the tissue pocket. The hardened material bioerodes in the pocket and releases the drug over a period of several days.

REFERENCES:
patent: 4764377 (1988-08-01), Goodson et al.
patent: 5620700 (1997-04-01), Berggren et al.

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