Inhibition of viral infection using antigen-binding proteins

Food or edible material: processes – compositions – and products – Products per se – or processes of preparing or treating... – With biocide or biostat

Reexamination Certificate

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C435S320100, C435S252300, C514S012200, C530S387100, C536S023530

Reexamination Certificate

active

07132121

ABSTRACT:
A method of inhibiting viral infection using a monovalent antigen binding protein comprising a single domain binding unit capable of binding to a virus is described. Preferably the protein is a heavy chain variable domain derived from an immunoglobulin naturally devoid of light chains. Food, pharmaceutical and cosmetic products comprising such proteins are also described together with a method for selecting inhibiting proteins from a large population of mainly containing non-inhibiting, but infectious agent binding fragments.

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Geller et al, J. Dairy Sci., 81:895-900 (Apr. 1998).
Muyldermans, Journal of Molecular Recognition, 12(2):131-140 (Mar.-Apr. 1999).

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