Inhibition of the binding human IgE to its receptor by tetracycl

Details Inhibition of the binding human IgE to its receptor by tetracycl Inhibition of the binding human IgE to its receptor by tetracycl

1997-12-29

1999-10-12

Fan, Jane

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549388, 514337, A61K 3135

Patent

active

059656050

ABSTRACT:
Disclosed are chemical agents with unexpected activity to inhibit the interactions between human immunoglobulin E (IgE) and its receptor (Fc.epsilon.RI) which interactions are known to be involved in triggering allergic responses. The agents may be used to module the allergic response in the treatment of various clinical conditions, including rhinitis, asthma, urticaria, atopic dermatitis, and anaphylacric shock. The agents can be formulated for oral, topical or parenteral administration.

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