Inhibition of hair growth

Details Inhibition of hair growth Inhibition of hair growth

1993-05-28

2001-05-29

Siegel, Alan (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S458000, C514S544000, C514S570000, C514S720000, C514S721000

Reexamination Certificate

active

06239170

ABSTRACT:

The invention relates to the inhibition of hair growth.
Arachidonic acid is released from membrane lipids in response to injury or other irritation. The enzyme 5-lipoxygenase converts arachidonic acid into 5-hydroperoxyercosa-6,8,11,14-tetraenoic acid, which subsequently is converted into a family of compounds known as leukotrienes. The exact biological role of leukotrienes has not yet been determined.
It has now been found that mammalian (including human) hair growth can be inhibited by applying to the skin a composition including an inhibitor of 5-lipoxygenase in an amount effective to reduce hair growth in the applied area.


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