INGAP protein involved in pancreatic islet neogenesis

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C530S350000, C530S412000, C435S069100, C435S069700, C514S012200, C514S013800, C514S014800, C424S198100

Reissue Patent

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RE039299

ABSTRACT:
Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display technique a cDNA clone expressed in cellophane wrapped but not in control pancreata was identified. Using this cDNA as a probe, a cDNA library was screened and a gene not previously described was identified and named INGAP.

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