Infectious bovine rhinotracheitis virus mutants, methods for the

Details Infectious bovine rhinotracheitis virus mutants, methods for the Infectious bovine rhinotracheitis virus mutants, methods for the

1987-11-08

1991-02-12

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

4351721, 4351723, 4353201, 935 9, 935 11, 935 12, 935 32, C12N 1500, C12N 700

Patent

active

049920510

ABSTRACT:
Infectious bovine rhinotracheitis virus (bovine herpesvirus type 1) mutants containing deletion and/or insertion mutations in a major viral glycoprotein gene, such that no antigenic polypeptides encoded by the viral gene are produced, vaccines for infectious bovine rhinotrachetis containing the same, methods for the production of the same and methods for use of the same. Animals vaccinated with these mutants do not develop antibodies to the viral glycoprotein and can be distinguished serologically from animals infected with infectious bovine rhinotracheitis virus field strains.

REFERENCES:
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Chemical Abstract: (Kitsuto et al., JP 62/118881 A2 May 30, 1987) #CA 109(7): 49612j.
Robbins et al., (1986) J. Virol. 59: 635-645.
Babuik et al., (1987) Virology 159: 57-66.

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