Indolocarbazole derivatives that stimulate platelet production

Details Indolocarbazole derivatives that stimulate platelet production Indolocarbazole derivatives that stimulate platelet production

1995-03-16

1997-02-18

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540545, A61K 3155, C07D49822

Patent

active

056042191

ABSTRACT:
Disclosed is an indolocarbazole derivative represented by the following formula (I), or a pharmaceutically acceptable salt thereof: ##STR1## [wherein R.sup.1 represents substituted or unsubstituted lower alkyl, R.sup.2 represents hydrogen, substituted or unsubstituted lower alkyl, R.sup.3 and R.sup.4 are the same or different, and represent hydrogen, nitro, NR.sup.5 R.sup.6, OR.sup.9, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl, or CH.dbd.NNR.sup.10 R.sup.11, W represents two hydrogen atoms or oxygen, and Me represents methyl, provided that when R.sup.1 is unsubstituted lower alkyl, R.sup.3 and R.sup.4 are not simultaneously hydrogen.

REFERENCES:
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patent: 5093330 (1992-03-01), Caravatti et al.
patent: 5344926 (1994-09-01), Murakata et al.
patent: 5455241 (1995-10-01), Wacker
Chemical Abstracts, vol. 115, No. 9 (Sep. 1991) p. 808 (92688z).
Hidaka et al., Ann. Rev. Pharmacol. Toxicol., vol. 32 (1992) 377:97.

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