Indolinone derivatives substituted in the 6-position, their...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

active

10625101

ABSTRACT:
The present invention relates to indolinone derivatives, substituted in the 6-position, of the formulain whichR1to R6and X are as defined in claim1,to their tautomers, enantiomers, diastereomers, to their mixtures and to their salts, in particular their physiologically acceptable salts, which have useful pharmacological properties, in particular in inhibiting action on various receptor tyrosine kinases and on the proliferation of endothelial cells and various tumour cells, to medicaments comprising these compounds, to their use and to processes for their preparation.

REFERENCES:
patent: WO 00/18734 (2000-04-01), None
patent: WO0018734 (2000-04-01), None
patent: WO 200018734 (2000-04-01), None
patent: WO0056710 (2000-09-01), None
patent: WO03026650 (2003-04-01), None
patent: WO03027102 (2003-04-01), None
patent: WO2004009547 (2004-01-01), None
Copy of the International Search Report for PCT/EP 03/07961.
Copy of International Search Report for Reference #PCT/EP03/07960.
A. Heckel, et al; Indolinone derivatives substituted in the 6 position, the preparation thereof and their use as pharmaceutical compositions; U.S. Serial No. 10624983; Filed Jul. 22, 2003.
J. Park, et al; Medicaments for the treatment or prevention of fibrotic diseases; U.S. Serial No. 11275226; Filed Dec. 20, 2005.

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