Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-04-07
1993-10-05
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514323, 546 16, 546201, C07D40112, A61K 31445
Patent
active
052505383
ABSTRACT:
Indole derivatives of formula (I) ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 may be hydrogen or lower alkyl optionally substituted by halogen; A.sup.1 represents a straight or branched alkylene chain containing from 2 to 4 carbon atoms; R.sup.5 is hydrogen or a straight or branched alkyl group; A.sup.2 is a straight or branched, saturated or unsaturated hydrocarbon chain containing from 2 to 6 carbon atoms; and R.sup.6 is selected from a group consisting of various structures, have been found to exhibit central nervous system activities.
REFERENCES:
patent: 4193927 (1980-03-01), Baumann et al.
patent: 4612312 (1986-09-01), Hibert et al.
patent: 4912115 (1990-03-01), Bomhard et al.
Glennon et al., J. Med. Chem vol. 32 (8), pp. 1921-1926 (Aug. 1989).
Andersen Peter H.
Farrup Peter
Hansen John B.
Hansen Louis B.
Jeppesen Lone
Brust Joseph Paul
Gabilan Mary Susan H.
Knudsen Sten L.
Lambiris Elias J.
Novo Nordisk A S
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