Indole derivatives

Details Indole derivatives Indole derivatives

1987-01-08

1989-08-08

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548504, A61K 3140, C07D21126, C07D21128

Patent

active

048553140

ABSTRACT:
Compounds are disclosed of formula (I): ##STR1## wherein R.sub.1 is halogen, a C.sub.1-3 alkoxy, R.sub.6 R.sub.7 NCO(CH.sub.2).sub.p --, R.sub.6 CONH(CH.sub.2).sub.p --, R.sub.6 R.sub.7 NSO.sub.2 (CH.sub.2).sub.p --, or R.sub.8 SO.sub.2 NH(CH.sub.2).sub.p -- (where R.sub.6 and R.sub.7 each represents hydrogen or C.sub.1-3 alkyl, R.sub.8 represents C.sub.1-3 alkyl and p is zero or 1);

REFERENCES:
patent: 3472870 (1969-10-01), Larsen et al.
patent: 4064255 (1977-12-01), Champseix et al.
patent: 4636521 (1987-01-01), Coates et al.
Handbook of Experimental Pharmacology, vol. XIX, Springer-Verlag, New York, 1966, pp. 126-129.
Sollmann, A manual of pharmacology 8th Ed., pp. 45-47.
Bradley et al., Proposals for the Classification and Nomenclature of Functional Receptors and 5-hydroxytryptamine, Neuropharmacology, vol. 25, No. 6, pp. 563-576, 1986.
Pharmacological Principles and Practice, Paton, pp. 1-2, 1968.
The Pharmacological Basis of Therapeutics, 7th Ed., pp. 35-37.
Evidence for Two Types of Excitatory Receptor for 5-hydroxytryptamine in Dog Isolated Vasculature, Apperley, pp. 215-223, Re J. Pharmac (1980).

Affiliated with

Also associated with

Rating

Indole derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Indole derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Indole derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-905845