Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-04-05
2005-04-05
Huang, Evelyn Mei (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S300000, C514S235500, C514S253040, C514S252010, C514S249000, C514S414000, C514S415000, C514S383000, C514S364000, C514S323000, C546S113000, C546S277400, C544S333000, C544S362000, C544S405000, C544S350000, C544S127000, C548S466000, C548S511000, C548S266400, C548S131000
Reexamination Certificate
active
06875770
ABSTRACT:
There is provided a compound represented by the general formula (1):wherein Het represents an optional substituted heterocylic group A1and A2each independently represent —CH═, etc.; A3represents —CH2—, etc.; R1represents a 4-fluorophenyl group, etc.; R2represents an alkyl group; n represents 0, 1 or 2, provided that when A1and A2both are —CH═, A3represents —CH2— or —SO2—, which is an indole derivative or a mono- or diazaindole derivative that has COX-2 inhibitory activity and is useful as a pharmaceutical, such as an anti-inflammatory agent, or addition salts thereof with a pharmaceutically acceptable acid or base, or hydrates thereof.
REFERENCES:
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patent: 0846689 (1997-12-01), None
patent: 7-215966 (1995-08-01), None
patent: 10-188066 (1998-06-01), None
patent: WO 9606840 (1996-03-01), None
patent: WO 9730030 (1997-08-01), None
Ishizawa Takenori
Kato Nobuaki
Maruyama Noriaki
Matsuoka Hiroharu
Suzuki Yukio
Browdy and Neimark , P.L.L.C.
Chugai Seiyaku Kabushiki Kaisha
Huang Evelyn Mei
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