Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-02-16
2009-11-03
Klinkel, Kortney L. (Department: 1611)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S350000, C546S113000, C548S469000
Reexamination Certificate
active
07612070
ABSTRACT:
There is provided a compound represented by the general formula (1):wherein Het represents an optional substituted heterocylic group A1and A2each independently represent —CH═, etc.; A3represents —CH2—, etc.; R1represents a 4-fluorophenyl group, etc.; R2represents an alkyl group; n represents 0, 1 or 2, provided that when A1and A2both are —CH═, A3represents —CH2— or —SO2—, which is an indole derivative or a mono- or diazaindole derivative that has COX-2 inhibitory activity and is useful as a pharmaceutical, such as an anti-inflammatory agent, or addition salts thereof with a pharmaceutically acceptable acid or base, or hydrates thereof.
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Brideau et al. Inflammation Research 1996, 45, 68-74.
Ishizawa Takenori
Kato Nobuaki
Maruyama Noriaki
Matsuoka Hiroharu
Suzuki Yukio
Browdy and Neimark PLLC
Chugai Seiyaku Kabushiki Kaisha
Klinkel Kortney L.
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