Indole-3-carboxamides as glucokinase activators

Details Indole-3-carboxamides as glucokinase activators Indole-3-carboxamides as glucokinase activators

2005-04-19

2005-04-19

Solola, Taofiq (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S139000, C548S492000

Reexamination Certificate

active

06881844

ABSTRACT:
The present invention provides glucokinase activators of formula I:wherein R1, R2and R3are defined in the specification. Glucokinase activators are useful for increasing insulin secretion in the treatment of type II diabetes.

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Khalaf et al.,Synthesis of novel DNA binding agents: indole containing analogs of bis-netropsin, 2000,Science Reviews Ltd.,6, pp. 264-265.

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