Inclusion complex of 7-isopropoxy-isoflavon formed with cyclodex

Details Inclusion complex of 7-isopropoxy-isoflavon formed with cyclodex Inclusion complex of 7-isopropoxy-isoflavon formed with cyclodex

1986-09-10

1989-05-02

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C08B 3716

Patent

active

048269638

ABSTRACT:
The invention relates to the inclusion complexes of 7-isopropoxy-isoflavone formed with cyclodextrin or cyclodextrin derivatives as well as to the pharmaceutical compositions containing these inclusion complexes as active ingredient. The invention further relates to the preparation of the new inclusion complexes. The new inclusion complex according to the invention shows higher dissolution and resorption properties as compared to the active ingredient administered per se.

REFERENCES:
patent: 3949085 (1976-04-01), Feuer et al.
patent: 4599327 (1986-07-01), Nogradi et al.
Fromming, "Cyclodextrin in Pharmaceutical Industry", -Proceedings of the First International Symposium on Cyclodextrins, Ed. J. Szejtli, D. Rgidel Publishing Co., London, England, 1981, pp. 367-376.
Controlled Drug Bioavailability, vol. 3, Edited by Victor F. Smolen and Luann Ball, John Wiley & Sons, pp. xii, xiii, Oct. 1984, Chapter 8, Molecular Entrapment and Release Properties of Drugs by Cyclodextrins J. Szejtli, pp. 365-421, (New York 1985).

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