Inclusion complex of 7-isopropoxy-isoflavon formed with cyclodex

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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536103, 549403, A61K 3172, C08B 3716

Patent

active

050433261

ABSTRACT:
The invention relates to the inclusion complexes of 7-isopropoxy-isoflavon formed with cyclodextrin or cyclodextrin derivatives as well as to the pharmaceutical compositions containing these inclusion complexes as active ingredient. The invention further relates to the preparation of the new inclusion complexes.
The new inclusion complex according to the invention shows higher dissolution and resorption properties as compared to the active ingredient administered per se.

REFERENCES:
patent: 3949085 (1976-04-01), Feuer et al.
patent: 4599327 (1986-07-01), Nogradi et al.
Fromming, "Cyclodextrin in Pharmaceutical Industry"--Proceedings of the First International Symposium on Cyclodextrin, ed. J. Szejtli, D. Reidel Publ. Co., London, England, 1981, pp. 367-376.
Szejtli, "Molecular Entrapment and Release Properties of Drugs by Cyclodextrins"--Controlled Drug Bioavailability, vol. 3, ed. Victor F. Smolen, John Wiley and Sons, New York, N.Y., 1985, pp. 365-421.

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