Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2007-10-26
2011-10-04
Desai, Anand (Department: 1656)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S471000, C435S468000, C435S300100, C435S350000
Reexamination Certificate
active
08030074
ABSTRACT:
The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.
REFERENCES:
patent: 6927042 (2005-08-01), Schultz et al.
patent: 7045337 (2006-05-01), Schultz et al.
patent: 7083970 (2006-08-01), Schultz et al.
patent: 7129333 (2006-10-01), Schultz et al.
patent: 7183082 (2007-02-01), Schultz et al.
patent: 7199222 (2007-04-01), Shultz et al.
patent: 7217809 (2007-05-01), Schultz et al.
patent: 7238510 (2007-07-01), Schultz et al.
patent: 7262040 (2007-08-01), Schultz et al.
patent: 7354761 (2008-04-01), Schultz et al.
patent: 7368275 (2008-05-01), Schultz et al.
patent: 7378263 (2008-05-01), Schultz et al.
patent: 7399619 (2008-07-01), Xie et al.
patent: 7432092 (2008-10-01), Schultz et al.
patent: 7494796 (2009-02-01), Alfonta et al.
patent: 7524647 (2009-04-01), Schultz et al.
patent: 7527943 (2009-05-01), Anderson et al.
patent: 7560535 (2009-07-01), Schultz et al.
patent: 7575895 (2009-08-01), Anderson et al.
patent: 7608423 (2009-10-01), Chin et al.
patent: 7638297 (2009-12-01), Anderson et al.
patent: 7638300 (2009-12-01), Schultz et al.
patent: 7642085 (2010-01-01), Schultz et al.
patent: 2004/0265952 (2004-12-01), Deiters et al.
patent: 2005/0009049 (2005-01-01), Chin et al.
patent: 2005/0136513 (2005-06-01), Zhang et al.
patent: 2005/0208536 (2005-09-01), Schultz et al.
patent: 2005/0250183 (2005-11-01), Schultz et al.
patent: 2006/0063244 (2006-03-01), Schultz et al.
patent: 2006/0073507 (2006-04-01), Deiters et al.
patent: 2006/0110784 (2006-05-01), Deiters et al.
patent: 2006/0110796 (2006-05-01), Schultz et al.
patent: 2006/0134746 (2006-06-01), Deiters et al.
patent: 2006/0160175 (2006-07-01), Anderson et al.
patent: 2006/0246509 (2006-11-01), Deiters et al.
patent: 2007/0009990 (2007-01-01), Alfonta et al.
patent: 2007/0111193 (2007-05-01), Zhang et al.
patent: 2007/0154952 (2007-07-01), Chin et al.
patent: 2007/0172915 (2007-07-01), Schultz et al.
patent: 2007/0178448 (2007-08-01), Tsao et al.
patent: 2007/0238152 (2007-10-01), Wang et al.
patent: 2007/0281335 (2007-12-01), Ryu et al.
patent: 2008/0044886 (2008-02-01), Wang et al.
patent: 2008/0064059 (2008-03-01), Schultz et al.
patent: 2008/0113407 (2008-05-01), Liu et al.
patent: 2008/0166766 (2008-07-01), Liu et al.
patent: 2008/0166783 (2008-07-01), Schultz et al.
patent: 2008/0167243 (2008-07-01), Schultz et al.
patent: 2008/0171317 (2008-07-01), Deiters et al.
patent: 2008/0176277 (2008-07-01), Chin et al.
patent: 2008/0213828 (2008-09-01), Schultz et al.
patent: 2008/0220472 (2008-09-01), Deiters et al.
patent: 2008/0227152 (2008-09-01), Schultz et al.
patent: 2008/0227153 (2008-09-01), Schultz et al.
patent: 2008/0227195 (2008-09-01), Chin et al.
patent: 2008/0233611 (2008-09-01), Schultz et al.
patent: 2008/0241903 (2008-10-01), Schultz et al.
patent: 2008/0261311 (2008-10-01), Schultz et al.
patent: 2009/0021511 (2009-01-01), Chen
patent: 2009/0028627 (2009-01-01), Gueret
patent: 2009/0053791 (2009-02-01), Schultz et al.
patent: 2009/0068717 (2009-03-01), Schultz et al.
patent: 2009/0081690 (2009-03-01), Deiters et al.
patent: 2009/0137424 (2009-05-01), Tsao et al.
patent: 2009/0148887 (2009-06-01), Brustad et al.
patent: 2009/0163368 (2009-06-01), Liu et al.
patent: 2009/0181429 (2009-07-01), Ryu et al.
patent: 2009/0181858 (2009-07-01), Deiters et al.
patent: 2009/0197339 (2009-08-01), Young et al.
patent: 2009/0208994 (2009-08-01), Seyedsayamdost et al.
patent: 2009/0209000 (2009-08-01), Wang et al.
patent: 2009/0227002 (2009-09-01), Schultz et al.
patent: 2009/0263376 (2009-10-01), Grunewald et al.
patent: 2009/0298119 (2009-12-01), Wang et al.
patent: 2009/0298124 (2009-12-01), Alfonta et al.
patent: 2010/0009425 (2010-01-01), Schultz et al.
patent: 2010/0021963 (2010-01-01), Liu et al.
patent: WO 2009/064416 (2009-05-01), None
patent: WO 2009/151491 (2009-12-01), None
Liu et al. Towards an organism with an expanded genetic code (Proc. Natl. Acad. Sci. vol. 96, pp. 4780-4785, 1999).
Payne et al (Transport and hydrolysis of antibacterial peptide analogues inEscherichia coli: Backbone modified Aminoxy Peptides. Journal of General Microbiology (1984), 130, 2253-2265).
Ames et al, Illicit transport, Oligopeptide permease. Proc. Nat, Ac. of Sc. (1973).
GenBank Accession No. 030250; Klenk et al. (May 30, 2000) The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaroglobus fulgidus, Retrieved from NCBI Nucleotide [online]; National Center for Biotechnology Information U.S. National Library of Medicine, Bethesda, MD, USA.
Coleman et al. (1986) “Enzyme-linked immunosorbent assay (ELISA) for detection of antibodies to protein-reactive drugs and metabolites: criteria for identification of antibody activity,”J. Immunol. Meth., 88(1):37-44.
Labarre et al.(1987) “Genetic analysis of amino acid transport in the facultatively heterotrophic cyanobacteriumsynechocystissp. strain,”J. Bacteriol., 169(10):4668-4673.
Novagen Protocol from online catalog, 5 pages, 1995.
Ohno et al. (2001) “Changing the amino acid specificity of yeast tyrosyl-tRNA synthetase by genetic engineering, ”J. Biochem., 130:417-423.
Anderson et al., Exploring the Limits of Codon and Anticodon Size,Chemistry and Biology, vol. 9, 237-244 (2002).
Azoulay et al., Glutamine analogues as Potential Antimalarials,.Eur. J. Med. Chem. 26, 201-5 (1991).
Bain et al., Biosynthetic site-specific Incorporation of a non-natural amino acid into a polypeptide,J. Am. Chem. Soc., 111:8013-8014 (1989).
Barton et al., Synthesis of Novel a-Amino-Acids and Derivatives Using Radical Chemistry: Synthesis of L-and D-a-Amino-Adipic Acids, L-a-aminopimelic Acid and Appropriate Unsaturated Derivatives.Tetrahedron Lett. 43, 4297-4308 (1987).
Boles et al.,Nat. Struct. Biol., 1:283 (1994).
Bradley et al., tRNA2GIn Su+2 mutants that increase amber suppression,J. Bacteriol. 145:704-712 (1981).
Brick et al.,J. Mol. Biol., 208:83-98 (1988).
Brunner, New Photolabeling and crosslinking methods,Annu. Rev. Biochem., 62:483-514.
Budisa et al.,Eur. J. Biochem., 230:788 (1995).
Budisa et al.,FASEB J. 13:41-51 (1999).
Budisa et al.,J. Mol. Biol., 270:616 (1997).
Budisa et al.,Proc. Natl. Acad. Sci. U S A, 95:455 (1998).
Christie & Rapoport, Synthesis of Optically Pure Pipecolates from L-Asparagine. Application to the Total Synthesis of (+)-Apovincamine through Amino Acid Decarbonylation and Iminium Ion Cyclization.J. Org. Chem. 50:1239-1246 (1985).
Cornish et al.,Angew. Chem. Int. Ed. Engl., 34:621 (1995).
Cornish et al.,J. Am. Chem. Soc., 118:8150-8151 (1996).
Craig et al., Absolute Configuration of the Enantiomers of 7-Chloro-4 [[4-(diethylamino)-1-methylbutyl]amino]quinoline (Chloroquine).J. Org. Chem. 53, 1167-1170 (1988).
Database NCBI, GenBank Accession No. E64348, Bult et al. ‘Complete genome sequence of the methanogenic archaeon,Methanococcus jannaschii,’ Gene Sequence, Jun. 3, 1996.
Doctor & Mudd,J. Biol. Chem., 238:3677 (1963).
Doring et al.,Science, 292:501 (2001).
Dougherty,Curr. Opin. Chem. Biol., 4:645 (2000).
Duewel et al.,Biochemistry, 36:3404 (1997).
Dunten & Mowbray, Crystal structure of the dipeptide binding protein fromEscherichia coliinvolved in active transport and chemotaxis.Protein Science4, 2327-34 (1995).
Ellman et al., Biosynthetic method for introducing unnatural amino acids site-specifically into proteins,Methods in Enz., 202:301-336 (1992).
Ellman et al., Site-specific incorporation of novel backbone structures into proteins,Science, 255:197-200 (1992).
England et al.,Cell, 96:89 (1999).
Fechter et al., Major tyrosine identity determinants inMethanococcus jannaschiiandSaccharomyces cerevisiaetRNATyr are conserved but expressed differently,Eur. J. Biochem. 268:761-767 (2001).
Francisco et al., Production and fluorescence-activated cell sorting ofEscherichia coliexpressing a functional antibody fragment on the external surface.Proc Natl Acad Sci U S A. 90:10444-8 (1993).
Francklyn et al. (2002) “Aminoacyl-tRNA synthetases: Versatile play
Anderson John Christopher
Chin Jason W.
Liu David R.
Magliery Thomas J.
Meggers Eric L.
Desai Anand
Gebreyesus Kagnew H
Littlepage Paul
Quine Intellectual Property Law Group P.C.
The Regents of the University of California
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