Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2004-06-04
2009-12-29
Kelly, Robert M. (Department: 1633)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007100, C435S008000
Reexamination Certificate
active
07638276
ABSTRACT:
The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising of the steps of: (a) compartmentalising genetic elements into microcapsules; (b) expressing the genetic elements to produce their respective gene products within the microcapsules; (c) sorting the genetic elements which produce the gene product having a desired activity. The invention enables the in vitro evolution of nucleic acids by repeated mutagenesis and iterative applications of the method of the invention.
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Griffiths Andrew
Tawfik Dan
454 Life Sciences Corporation
Elrifi, Esq. Ivor R.
Hiriyanna Kelaginamane
Kelly Robert M.
Mintz Levin Cohn Ferris Glovsky and Popeo PC
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