In-vitro method for testing bioequivalence of iron-sucrose...

Chemistry: analytical and immunological testing – Metal or metal containing – Mn – te – re – fe – ru – os – co – rh – ir – ni – pd – pt

Reexamination Certificate

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C436S073000, C436S094000, C436S100000

Reexamination Certificate

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08058076

ABSTRACT:
The present disclosure relates to an in vitro method for measuring the T75of reduction kinetics of iron from Fe+3to Fe+2in an iron-sucrose complex and hence assessing the bioequivalency of iron-sucrose composition. According to the disclosed method, T75of reduction kinetics of iron in an iron-sucrose complex in between 25 to 50 minutes indicates bioequivalent iron-sucrose composition.

REFERENCES:
patent: 5624668 (1997-04-01), Lawrence et al.
patent: 6911342 (2005-06-01), Helenek et al.
patent: 6960571 (2005-11-01), Helenek et al.
patent: 7169359 (2007-01-01), Helenek et al.
patent: 7754702 (2010-07-01), Helenek et al.

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