Implantable cells that alleviate chronic pain in humans

Details Implantable cells that alleviate chronic pain in humans Implantable cells that alleviate chronic pain in humans

1995-01-27

1997-08-12

Stone, Jacqueline M.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424563, 424570, 424520, 514 44, 604 49, C12N 1500, A61K 3530, A61K 4800, A61F 266

Patent

active

056562675

ABSTRACT:
This invention provides a method of alleviating chronic pain in humans. Viable, implantable cells are selected which release neuroactive substances that reduce chronic pain. The cells are cultured to improve their viability, and administered into a region of the central nervous system of a patient who is suffering from chronic pain. The cells continue to secrete the neuroactive substances within the patient without exogenous stimulation. Suitable implantable cells include adrenal medullary tissue cells, chromaffin cells or genetically engineered cells.

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