Immunological combination compositions and methods

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fusion protein or fusion polypeptide

Reexamination Certificate

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C424S193100, C424S197110, C424S200100, C424S201100, C424S203100, C424S234100, C424S237100, C424S244100, C435S069100, C435S069300, C435S069700, C435S071100, C530S350000

Reexamination Certificate

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11173364

ABSTRACT:
Immununological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader for lipidation and PspA for the protein portion. The antigen can be OspC and the lipoprotein OspA. The components of the composition are co-administered. A potentiated immunological response is obtained by the compositions and methods.

REFERENCES:
patent: 93/07897 (1993-04-01), None

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