Immunoglobulins devoid of light chains

Details Immunoglobulins devoid of light chains Immunoglobulins devoid of light chains

1995-06-06

2000-01-18

Eisenschenk, Frank C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435243, 4353201, 435326, 435348, 435363, 5303873, 536 2353, C12N 701, C12N 1563, C12P 2108, C07H 2104

Patent

active

060156953

ABSTRACT:
There is provided an isolated immunoglobulin comprising two heavy polypeptide chains sufficient for the formation of a complete antigen binding site or several antigen binding sites, wherein the immunoglobulin is further devoid of light polypeptide chains.

REFERENCES:
Webster's II New Riverside University Dictionary, The Riverside Publishing Co./Houghton Mifflin Co., Boston, MA, 1995.
Hamers-Casterman et al., "Nature", 363:446-48 (1993).
Roitt et al., "Immunology", Gower Medical Publishing, London, pp. 1.5 and 5.7 (1985).
Ward et al., "Nature", 341:544-546 (1989).
Blier et al., "A Limited Number of B Cell Lineages Generates The Heterogeneity Of A Secondary Immune Response", J. Immunology, vol. 139, No. 12, pp. 3996-4006 (Dec. 15, 1987).

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