Immunogenic chimeras comprising nucleic acid sequences encoding

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4241851, 4242041, 4242341, 4242651, 4242771, 514 2, 530300, A61K 3900, A61K 3802, C07K 200

Patent

active

057335486

ABSTRACT:
Immunogenic chimeric proteins comprising an endoplasmic reticulum signal sequence and at least one other peptide are disclosed. The invention relates to the design of vaccinia virus constructs capable of directing host organism synthesis of immunogenic chimeric proteins which can be used as immunogens, as vaccines, or in methods of treatment for cancer, infectious diseases, or autoimmune diseases.

REFERENCES:
patent: 5098833 (1992-03-01), Lasky et al.
Rouse et al. (1988) Antiviral cytotoxic T lymphocyte induction and vaccination. Rev. Infect. Dis. 10:16-33. Jan. 1988.
Wooden et al. (1988) Exp. Cell Res. 178:84-92.
Prince et al. (1990) Mol. Biochem. Parasitol. 43:97-106.
Eisenlohr, L.C. et al., (1992) Cell 71:963-972.
Eisehlohr, L.C. et al., (1992) J. Exp. Med. 175:481-487.
Anderson, K. et al., (1991) J. Exp. Med., 174:489-492.
Trowsdale, et al., (1990) Nature, 348:741-744.
Monaco, J.S., et al., (1990) Science 250:1723-1726.
Townsend, A.R.M., et al., (1984) Cell 39:13-25.
Deverson, E., et al., (1990) Nature, 748:738-741.
Spies, T., et al., (1990) Nature, 348:744-747.
Yewdell, J.W., et al., (1988) Science 239:637-640.
Bennink, J.P., et al., (1982) Nature 296:75-76.
Yewdell, J.W., et al., (1985) Proc. Natl. Acad. Sci. USA, vol. 82, pp. 1785-1789.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Immunogenic chimeras comprising nucleic acid sequences encoding does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Immunogenic chimeras comprising nucleic acid sequences encoding , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunogenic chimeras comprising nucleic acid sequences encoding will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-49165

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.